I would prefer Nylander/Gagne. Reasons why.
I am not completely sold on Sykora. Spezza is a band-aid boy but probably will put up 90+ points if healthy.
I loveeeeee Gagne this year, I really see him breaking the 50 goal season. I personally think he did pretty good last year on a horrible Flyers team. I really have no opinion on Nylander other than he will be feeding AO the puck, that has to be worth something. I see him hovering around 75-80 points but could be higher if AO and himself click.