Since you own both Spezza and Filatov in your' Sig I guess it must be for another league.
I think this would depend on what stage your' team is at. Spezza is the safe bet, he's a top end player and he is just entering his prime. The prospects that are being offered are pure potential, and inn all likelyhood will not be seriously impacting your fantasy roster for 2-3 seasons. So, if you are in a position where you are contending now and have a roster built for that I'd stay with Spezza. If you are in the rebuild process and do not expect to compete for 2-3 seasons when all of your young guys are hitting their strides, take one of the trades. Of the two I would probably prefer Seguin to Eberle as well.